Polymyositis With Intersititial Lung Disease

Interstitial Lung Disease in Polymyositis and Dermatomyositis

Objectives. To assess prevalence, characteristics, and long-term outcome of interstitial lung disease (ILD) in polymyositis (PM) and dermatomyositis (DM). To determine predictive variables of ILD course in PM/DM, and to define both clinical and biochemical features associated with ILD onset in PM/DM. Methods. The medical records of 156 consecutive PM/DM patients in 3 medical centers were review...

Tacrolimus in refractory polymyositis with interstitial lung disease.

A Case of Polymyositis with Interstitial Lung Disease Onset.

Polymyositis is an idiopathic inflammatory myopathy of unknown aetiology that affect skeletal muscles causing symmetrical, proximal muscle weakness, and also other internal organs. The investigations reveal elevated skeletal muscle enzyme levels and characteristic electromyography (EMG) and muscle biopsy findings. Pulmonary involvement in polymyositis includes respiratory muscle weakness, aspir...

Recurrent polymyositis-associated lung disease after lung transplantation.

The association between interstitial lung disease and polymyositis/dermatomyositis is well known. It severely affects patients' quality of life, worsens prognosis and represents a major risk factor for premature death. Current treatment is unclear and therapeutic options are based on case series. We report the case of a 15-year old female diagnosed with end-stage lung disease associated to poly...

Polymyositis associated with Hodgkin's disease.

Introduction Polymyositis occurring in patients over the age of 40 years is associated with a high incidence of malignancy (Pearson and Currie, 1974). The tumour is most frequently a carcinoma arising from the bronchus, prostate, breast, ovary, uterus or gastrointestinal tract but may remain undiagnosed in spite of extensive investigations (Pearson and Currie, 1974). The authors wish to report ...